A Case of 21-hydroxylase Deficiency with Massive Bilateral Adrenal Masses

Background: Congenital adrenal hyperplasia (CAH) can lead to bilateral tumors. Excess adrenocorticotropic hormone is thought play a role in the development of nodules. Here we present patient with simple virilizing form 21-hydroxylase deficiency, married man, tumors, and 46-XX chromosomes.Case report: 39-year-old man suffered from abdominal pain tension. Abdominal tomography showed macronodular both glands, largest nodule reaching 4.2 cm on left side. The patient's old records that CAH had been diagnosed at age 11 years, but was not taking any medication. treated glucocorticoid. Despite irregular use treatment, size nodules remained stable for 3 then significant reduction observed.
 Conclusion: In patients masses incidentaloma, should be considered avoid unnecessary surgery or biopsy. A 17-hydroxyprogesterone test suspicious useful tool diagnosis.